Monday, March 11, 2019
The Discovery of DNA
It is amazing how important things atomic number 18 being spy by persons who spend most of their lives dedicated to research. It is by chance more amazing how a scientist discovers hotshot thing while difficult to discover other things. Imagine if no one was patient full to conduct experiments to prove their assumptions. If that was the case, we would not know today that DNA is the familial material. This paper will discuss how DNA was discovered, its bodily structure and the scientists who contributed to the discovery.Deoxyribonucleic acid (DNA) is considered as the molecular blueprint of life that quite a little be passed to the next generation. It was discovered in 1953 (University of Georgia, 2007) from experiments seeking to understand bacterial pneumonia which claimed many lives during the twentieth century. During these experiments, researchers stumbled into discoveries which afterward on became the reagents for promote experiments leading to the discovery of DNA as the transmissibleal material (OConnor, 2008).DNA looks uniform a twisted ladder wherein rungs are secured by twain a modality of quaternity molecules that are interlocking. These molecules are nucleic acid bases. The four molecules include thymine, adenine, cytosine, and guanine (University of Georgia, 2007). Certain scientists have been notable for conducting experiments leading to the discovery of DNA. One of these was Oswald Avery whose team was trying to find taboo how to treat lobular pneumonia. From his experiments, he proved that DNA indeed carries genetic information.During that time, many great deal believed that the gene would be made up of protein and not nucleic acid (WGBH, 1998). some other scientist which contributed to DNA discovery was Frederick Griffith who, in 1928, conducted an experiment utilizing pneumonia bacteria and mice. Recent studies pointed that Griffiths experiment was one of many others hinting that DNA was the hereditary material. Griffith assu med from his experiment, wherein he used a smooth (S) and rough (R) communication channels of Streptococcus pneumoniae on a mice, that polysaccharide coating was the cause of the illness to the mice.Further into his experiment, he found verboten that something in the living cell, and not the polysaccharides, caused the disease. Later on he speculated that the R strain bacteria he injected into the mice has absorbed the dead S strain bacterias genetic material. Furthermore, he speculated that the protein contained in the chromosomes was not the genetic bacteria due to the finding that heat denatures protein (Biology at Clermont College, n. d. ). At first, Avery was speculative of the results of Griffiths experiment. However, other researchers further studied Griffiths findings.In 1931, Sia and Dawson found out that transformation, a process wherein one strain absorbs the genetic material of some other strain and becomes that bacterium, could also take place in liquid cultures of pneumococci and mice. In 1948, Linus Pauling found out that proteins are shaped in alpha helix, which looks like a spring coil. Another significant discovery took place two years later, when Erwin Chargaff discovered an important foundation of the description of DNA north bases in DNA varied, but some bases occur in one-to-one ratio.Paulings findings have further aroused interest into two researchers, videlicet Francis Crick and James Watson. They were not the only ones interested in analyze DNA. Maurice Wilkins and Rosalind Franklin from London were also studying DNA. Franklin discovered the possibility that DNA can occur in two forms. It depends on the humidity of the air. Franklin figured out that the molecules phosphate was located on the outside. Watson and Crick, determined to get their studies after a failed model, conceptualized that there are two chains of nucleotides in the molecule.These two chains were in a helix, as what Franklin has discovered, but one chain was mo ving to the opposite direction of another. Furthermore, they believed that the strands of DNA molecule served as the template for the other. The strands separate during cell division. In addition, a new half(a) is built on each strand. The team found out that this was the way DNA reproduces without change in its structure (WGBH, 1998). The discovery of DNA was considered as the most important biological work and it has paved the way for further experiments and studies. Crick and Watson won the Nobel Prize for their findings.ReferencesBiology at Clermont College. (n.d). DNA structure and function. Retrieved January 30, 2009, from http//biology.clc.uc.edu/courses/bio104/dna.htmOConnor, C. (2008). Discovery of DNA as the hereditary material utilise Streptococcus pneumoniae. Nature Education, 1(1).University of Georgia. (2007). Study suggests how DNA building block qualification have formed. Retrieved January 30, 2009, from http//www.world-science.net/othernews/071102_adenine.htmWGBH . (1998). Watson and Crick describe structure of DNA. Retrieved January 30, 2009, from http//www.pbs.org/wgbh/aso/databank/entries/do53dn.html
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